Faster Short Tandem Repeat (FaSTR) Human Deoxyribonucleic Acid (DNA) Profiling System
Abstract
Previous rapid DNA analysis systems have relied on pneumatics and mechanical valves for microfluidic movement. Current systems are comprised of bulky hardware and DNA analysis times greater than 60 minutes. The FaSTR DNA instrument exploits centrifugally-driven microfluidics to eliminate mechanical valves and pressure-driven flow, and allows commercial-off-the-shelf electronics to facilitate sample preparation, polymerase chain reaction, and assessment. This paradigm shift to microfluidic technology radically reduces the form factor, analysis time, and cost of the system. The FaSTR project will produce the first truly portable, rapid DNA analysis instrument capable of generating DNA profiles from “sample in” to “answer out” in less than 30 minutes and provide a match probability of 1 in 55 billion people.
Document Details
- Document Type
- Accomplishment
- Publication Date
- Oct 01, 2019
- Source ID
- 61300d807a170f0d6805babd4fc5b12e