Biological Adaptation, Assembly and Manufacturing
Abstract
(U) The Biological Adaptation, Assembly and Manufacturing program will examine the structure, function, and informational basis underlying biological system adaptation, and the factors employed by the organism to assemble and manufacture complex biological subsystems. The unique stability afforded biological systems in their ability to adapt to wide extremes of physical and endurance (e.g., heat, cold, and sleeplessness) parameters will be examined and exploited in order to engineer stability into biological systems required for the military (such as blood, bioengineered tissues or other therapeutics). In addition, the fault tolerance present in biological systems will be exploited in order to assemble and manufacture complex physical and multi-functional systems, both biological and abiotic (such as tissue constructs designed for reconstructive surgery). These systems include novel load-bearing bio-interactive materials and composites for repair of severe hard tissue trauma, including complex bone fractures. A key new antibody technology will develop the ideal antibody master molecule for use in unattended sensors that maintains high temperature stability and controllable affinity for threat agents. Applications to Defense systems include the development of chemical and biological sensors, and improved battlefield survivability of the warfighter.
Document Details
- Document Type
- Accomplishment
- Publication Date
- Oct 01, 2011
- Source ID
- 6cc8f71a70d29520738e412938d94755