In vivo Nanoplatforms (IVN)

Abstract

The In vivo Nanoplatforms (IVN) program seeks to develop the nanoscale systems necessary for in vivo sensing and physiologic monitoring and delivery vehicles for targeted biological therapeutics against chemical and biological (chem-bio) threat agents. The nanoscale components to be developed will enable continuous in vivo monitoring of both small (e.g. glucose, lactate, and urea) and large molecules (e.g. biological threat agents). A reprogrammable therapeutic platform will enable tailored therapeutic delivery to specific areas of the body (e.g. cells, tissue, compartments) in response to traditional, emergent, and engineered threats. The key challenges to developing these systems include safety, toxicity, biocompatibility, sensitivity, response, and targeted delivery. The IVN program will have diagnostic and therapeutic goals that enable a versatile, rapidly adaptable system to provide operational support to the warfighter in any location.

Document Details

Document Type
Accomplishment
Publication Date
Oct 01, 2015
Source ID
95762e03d25f9a374cb53cdb0168f3c5

Tags

Fields of Study

  • Biology

Readers

  • Cardiovascular Physiology
  • Critical Infrastructure Protection in CBRN and WMD Threats.
  • Nanocomposite Materials Science

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