ANTIGENIC STUDIES ON INFLUENZA VIRUS

Abstract

A study was made of relationships between tissue culture and influenza virus with radioactive phosphorus as the indicator system. Lee, PR8, and Thompson influenza virus strains were absorbed and eluted from normal chicken red blood cells (rbc's). When a constant amount of inorganic radioactive phosphorus was added to the rbc's, the virus-treated cells acquired more phosphorus than cells treated with normal allantoic fluid. The yolks of 7-day- old chick embryos were inoculated with radioactive phosphorus. The embryos were then reincubated for 5 days, after which the rbc's were removed. Treatment of the rbc's with virus and with normal allantoic fluid resulted in no difference with respect to the release of phosphorus from the surface of the cell.

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Document Details

Document Type
Technical Report
Publication Date
Jan 01, 1953
Accession Number
AD0006423

Entities

People

  • Thomas G. Ward

Organizations

  • Johns Hopkins University

Tags

DTIC Thesaurus Topics

  • Blood
  • Blood Cells
  • Cells
  • Great Lakes
  • Indicators
  • Influenza
  • Materials
  • Neutralization
  • Phosphorus
  • Serodiagnosis
  • Tissue Culture
  • Tissue Culture Cells
  • Virion
  • Viruses

Fields of Study

  • Biology

Readers

  • Environmental Engineering
  • Virology (or Medical Virology).