THE EFFECT OF IRRADIATION ON AUTOLOGOUS SKIN TRANSPLANTS

Abstract

Localized irradiation in large enough dosage prejudices successful autologous skin transplantation in the rabbit. It appears that the deleterious effects of irradiation in this respect are first manifested in the graft itself; at higher doses, damage to the recipient site prevents takes. At the qualities of irradiation used in these experiments (HVL 0.31 mm Al and 2.2 mm Al), 2200r to the donor skin prevented successful grafting whereas this dose to the recipient site showed no significant diminution in per cent of graft takes as compared to control levels. Administration of cysteine intravenously just before irradiation afforded partial protection to the donor skin. (Author)

Document Details

Document Type
Technical Report
Publication Date
Apr 01, 1961
Accession Number
AD0255943

Entities

People

  • Daniele Salvioni
  • Milton Elkin

Organizations

  • Jefferson Einstein Hospital

Tags

DTIC Thesaurus Topics

  • Amino Acids
  • Amino Acids Peptides And Proteins
  • Anatomy
  • Behavior And Behavior Mechanisms
  • Behavioral Disciplines And Activities
  • Behavioral Sciences
  • Biological Sciences
  • Biomolecules
  • Body Regions
  • Chemical Compounds
  • Cysteine
  • Neutral Amino Acids
  • Prejudice
  • Psychology
  • Social Psychology
  • Transplantation
  • Transplants

Fields of Study

  • Medicine

Readers

  • Immunology
  • Nuclear and Radiation Engineering.
  • Trauma Surgery or Emergency Medicine.

Technology Areas

  • Biotechnology