STUDY OF SPREADING OF SOLUTIONS ON CUTANEOUS SURFACES AND PENETRATION INTO SKIN

Abstract

Four mechanisms which may be active in preventing the penetration of ionic surfactants through excised human skin are: (1) physical and chemical structures and reactions which make difficult the establishment of a continuous aqueous pathway through the skin, (2) steric hindrance, (3) electrostatic repulsion, and (4) combination of surfactants with proteins in the stratum corneum. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jun 12, 1961
Accession Number
AD0258341

Entities

People

  • Edith Gould
  • Irvin H. Blank

Organizations

  • Massachusetts General Hospital

Tags

DTIC Thesaurus Topics

  • Anatomy
  • Biological Sciences
  • Epidermis
  • Skin
  • Surface Active Substances

Readers

  • Analytical Chemistry
  • Breast cancer cell signaling and growth regulation.
  • Toxicology/Environmental Toxicology