ELECTROPHORETIC PATTERNS WITH X-IRRADIATED BLOOD SERUMS

Abstract

Electrophoretic patterns of blood serums after in vitro irradiation show marked decreases in the concentration of albumin and gamma globulin. These changes are accompanied by compensatory increases in the beta and alpha components. It is postulated that perhaps albumin and gamma globulin molecules are altered by irradiation so that they become electrophoretically indistinguishable from alpha and beta proteins. Increases in biuret values were found only in human blood plasma and serum after in vitro doses of 2.54 x 106 r. Electrophoretic changes produced by in vitro irradiation of serum with massive doses parallel those changes observed after in vivo exposure to lethal and sublethal doses. (Author)

Document Details

Document Type
Technical Report
Publication Date
Aug 10, 1961
Accession Number
AD0263253

Entities

People

  • A.j. Luzzio

Organizations

  • United States Army Medical Research Laboratory

Tags

DTIC Thesaurus Topics

  • Blood
  • Blood Plasma
  • Blood Serum
  • Gamma Globulin
  • Globulins
  • Macromolecules
  • Molecules
  • Polymers
  • Proteins

Fields of Study

  • Biology
  • Computer science
  • Medicine
  • Physics

Readers

  • Immunology
  • Molecular and Cellular Biochemistry
  • Nuclear and Radiation Engineering.