MECHANISM OF ENZYME ACTION
Abstract
THE SUCCESSFUL SYNTHESIS OF 5(OR 6)-VINYL BENZIMIDAZOLE IS DESCRIBED. This monomer was prepared via a route which started with beta(4-formanilino)-ethyl formate. The final step was dehydrochlorination of 5(or 6)-(betachloroethyl)-benzimidazole. Structure of the monomer was proven by elemental analysis, derivatives, hydrogenation and ozonolysis. Attempts to prepare copolymers of 4-vinyl imidazole and allyl alcohol by reduction of the methyl acrylate copolymers are described. Also reported are attempts to prepare 1-methyl-4 (or 5)-vinyl imidazole and copolymers of 4-vinyl imidazole and vinylene carbonate. The successful synthesis of copolymers with acrylic acid and of poly(4-vinyl imidazole) are reported. Some kinetic studies of the hydrolysis of p-nitrophenyl acetate catalyzed by imidazolecontaining polymers are reported. All polymers tested were slower than imidazole itself. It is concluded that no enhancement of catalytic activity was found in the few polymers tested. The synthesis of new polymers is in progress. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 30, 1961
- Accession Number
- AD0264911
Entities
People
- Bernhard Kosters
- C.g. Overberger
- Norman Vorchheimer
Organizations
- New York University Tandon School of Engineering