GLUCOSE UPTAKE AND DISSIMILATION BY X-IRRADIATED, STRAVED, AND DIVISION INHIBITED YEAST
Abstract
Estimates of the relative participation of the pentose cycle and the Embden-Meyerhof-Parnas pathways in sugar dissimilation, by means of C14O2 recoveries from yeast cells fed specifically labeled glucose, showed significant differences indicating less pentose cycle activity in starved irradiated cells than in unirradiated cells. This result is in qualitative agreement with previously observed R.Q. values, which indicated greater glycolytic activity in starved irradiated cells, and thus implicates a change in pathways of dissimilation in the response observed following irradiation and starvation. A concurrent lower rate of glucose uptake from the medium was observed for unirradiated, starved cells as compare to irradiated cells. The possibility that the membrane is the site of the cellular change involved in these responses was discussed. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 16, 1961
- Accession Number
- AD0264976
Entities
People
- Edward Spoerl
- W. Quiner
Organizations
- United States Army Medical Research Laboratory