TOLERANCE TO ANOXIA AND THE DEVELOPMENT OF CEREBRAL SUCCINIC DEHYDROGENASE AND CYTOCHROME OXIDASE ACTIVITIES IN THE RABBIT
Abstract
Cerebr l succinic dehydrogenase and cytochrome o idase activities were measur d in rabbit varying in age from les than 24 hours to adulthood. The activities of both enzymes are quite low at birth, but gradually increase to adult levels 15 to 18 days postn tally. The time at which adult levels of enzyme activity are reached coi ci s with the critical period of growth as described by Schade and Baxter (Exp. Neurol. :158, 1960) and Flexner. (Enzymatic and functional patterns of the developing m mmalian brain. In Waelsch, H. (ed.) Biochemistry of the d veloping nervous system, p. 281. New York: Academic Press, 1955.) The critical period for evelopmen of the oxidative enzymes studied coincides with the time at which th developi g rabbit becomes least resistant to a oxia. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Sep 01, 1961
- Accession Number
- AD0265262
Entities
People
- C.s.jr Herron
- S. Cassin
Organizations
- United States Air Force School of Aerospace Medicine