Further Studies on Reduction of X-Irradiation Mortality of Guinea Pigs by Plant Materials

Abstract

Exposure to 400 r of whole-body X-irradiation resulted in 97 percent mortality in 10 to 15 days among young male guinea pigs fed a basal diet of bran and oats plus ascorbic acid. Supplementation with alfalfa or broccoli, for two weeks before irradiation and during 30 days after irradiation reduced mortality and extended survival time. Although supplementation of an adequate purified diet with broccoli or alfalfa promoted superior weight gain, radiosensitivity was unaffected under these conditions. The beneficial effect of green plant supplementation could not be duplicated by feeding a mixture of 48 chemically-defined ingredients patterned upon the composition of broccoli, in conjunction with the bran-oats diet. The radioprotective agent(s) in alfalfa was water-soluble.

Open PDF

Document Details

Document Type
Technical Report
Publication Date
Nov 01, 1961
Accession Number
AD0268538

Entities

People

  • A. H. Munson
  • Doris H. Calloway
  • W. K. Calhoun

Tags

DTIC Thesaurus Topics

  • Amino Acids
  • Animals
  • Body Weight
  • Chemistry
  • Digestive System Processes
  • Engineering
  • Food
  • Health Services
  • Materials
  • Meals
  • Nutrition
  • Ores
  • Plant Oils
  • Rodents
  • Standardization
  • Vegetables
  • Vitamin C

Readers

  • Nuclear and Radiation Engineering.
  • Toxicology/Environmental Toxicology
  • Women's Health and Cancer Risk Research: African American Women and Pregnancy Outcomes.