NUTRITION AND CIRRHOSIS OF THE LIVER
Abstract
Regeneration of the liver and iron diseases of the liver were studied, principally using radioisotope and autoradiographic techniques. (1) A search was made for a possible humoral factor in the blood of rats that controls regeneration of the liver after partial hepatectomy. (2) Obstruction of the common bile duct of the rat was found to result in regeneration of liver cells comparable in number to that seen approximately 48 hours after partial hepatectomy in addition to well known changes in bile ducts. (3) In experimental carcinoma of the liver produced by feeding a butter yellow derivative, an increased regeneration of lever cells did not precede the occurrence of tumors. (4) Regeneration of the cirrhotic liver produced by dietary means was compared with regeneration of normal rat liver, in both cases following partial hepatectomy. Cirrhotic liver responded at the same times and to the same extent as normal liver. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 31, 1961
- Accession Number
- AD0269231
Entities
People
- G. Kenneth Mallory
- Richard A. Macdonald
Organizations
- Harvard University