CHLOROTHIAZIDE ATTENUATION OF THE PRESSOR RESPONSES TO EPINEPHRINE, LEVARTERENOL, AND ANGIOTENSIN IN THE PERFUSED RENAL VASCULAR BED
Abstract
A study was made to investigate the effect of acute local chlorothiazide administration on renal vascular resistance and to ascertain if chlorothiazide alters the pressor response to vasoactive agents. Chlorothiazide did not ACUTELY ALTER RENAL VASCULAR RESISTANCE. The pressor responses to epinephrine, levarterenol, and angiotensin were attenuated and the depressor response to magnesium chloride (MgCl2) was potentiated. Acute local administration of chlorothiazide in the perfused renal vascular bed of the dog acutely alters the pressor response to certain vasoactive agents. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 10, 1961
- Accession Number
- AD0270485
Entities
People
- Edward D. Frohlich
- Jay Y. Gillenwater
- Jerry B. Scott
Organizations
- United States Army Medical Research Laboratory