HISTOPATHOLOGICAL STUDIES OF TISSUE REACTIONS TO VARIOUS METALS IMPLANTED IN CAT BRAINS
Abstract
Metal rods of gold, platinum, silver, stainless steel, tantalum, and tungsten were implanted in cat brain tissue. The resulting changes were observed for as long as 6 months. The stainless steel and gold rods caused the least reaction while platinum and tantalum caused a slightly greater response. The lesions resulting from tungsten were comparatively more extensive. Silver elicited a violent tissue response with the astrocytic reaction extending to 3.75 mm in diameter in a lesion produced by a 7-day implantation. This evidence indicates a preference of metals to be used in the fabrication of intracerebral electrodes from the standpoint of tissue reaction. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 1961
- Accession Number
- AD0271593
Entities
People
- Farrel R. Robinson
- Marion T. Johnson