THE CORONARY HEMODYNAMIC RESPONSE TO ENVIRONMENT
Abstract
Positive pressure breathing with 100 percent oxygen in dogs wearing bladder-type partial pressure suits causes major reduction in the cardiac output despite equal counter pressure to the respiratory passageway and the absence of pulmonary hyperinflation. These experiments were carried out to investigate the possibility that the circulatory defect was a consequence of defective myocardial perfusion. The experimental work revealed that coronary blood flow was significantly reduced in dogs wearing the pressure suit. The reduction in coronary flow was insignificantly less than the reduction in cardiac output and the coronary resistance was increased. This is in contrast with what is observed when the primary circulatory defect is one of the failure of venous return. This suggests that major circulatory difficulty encountered in the pressure suit used may be a consequence of coronary vasoconstriction as a primary event. The circulatory failure which occurs in the pressure suit may be of cardiac rather than peripheral origin.
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 01, 1961
- Accession Number
- AD0273513
Entities
People
- Eric Ogden
- Leo A. Sapirstein
Organizations
- Ohio State University