THE SEROLOGICAL SPECIFICITY OF RADIATION ALTERED HUMAN SERUM GAMMA GLOBULIN
Abstract
Human serum gamma globulin after intense in vitro X-irradiation was used as an antigen to obtain antiserums in goats. It was found to be distinct immunologically from non-irradiated or heated human serum gamma globulin by quantitative precipitin tests and possessed a slow moving component as determined by paper strip electrophoresis. Similar antigens were produced by irradiating human serum in vitro with low doses. Preliminary evidence points to the possibility of detecting irradiation-altered proteins in the irradiated patient by quantitative immunological methods. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 19, 1962
- Accession Number
- AD0275973
Entities
People
- Anthony J. Luzzio
Organizations
- United States Army Medical Research Laboratory