INTRANEURONAL MECHANISMS FOR INFORMATION STORAGE. THE BIOCHEMICAL RELATIONSHIP BETWEEN NEURON AND GLIA
Abstract
A conspicuous feature of the neurons is their capacity to produce ribonucleic acids (RNA) and proteins on a large scale. This activity was as characteristic of neurons as is the generation of bioelectric potentials and is intimately linked with the specialized nervous function. When the stimulation of a group of neurons is increased, production of RNA and proteins also increases. The neuron is structurally and niochemically similar to an enormous gland cell. Sensory deprivation showed that stimuli are equally important for the maintenance of the nervous function during the life cycle. An intimate morphological relationship between the glial cells and the neurons is discussed. A distinction was made between neutronal glia (mainly oligodendrocytes) and capillary glia (mainly astrocytes). On stimulation, glial potentials have been obtained which are 700 to 1000 times slower than those generated by the neurons. In cultures glial cells have been observed to climb along neurons like spiders, suggesting a pronounced affinity. The glia have been shown to exhibit pinocytosis and to react with structural changes earlier than did the neurons under experimental conditions. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 20, 1962
- Accession Number
- AD0276234
Entities
People
- Holger Hyden
Organizations
- University of Gothenburg