THE CHEMISTRY OF RYANODINE.
Abstract
Structure studies were carried out on ryanodine, an alkaloid which causes irreversible muscle contraction. Hydrolysis gives ryanodol and 2-pyrrolecarboxylic acid. Ryanodol was oxidized by periodic acid to give a crystalline, three-mole oxidation product. Ryanodol also was reduced by P and HI to a crystalline, benzenoid gamma-lactone. Aromatization studies on these products yielded a series of naphthalenes and anthracenes. A number of 2-pyrrolecarboxylic esters were prepared from 2-pyrrolecarboxylic acid chloride and the corresponding alcohol. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 01, 1962
- Accession Number
- AD0277818
Entities
People
- Henry Rapoport
Organizations
- University of California, Berkeley