EFFECT OF ACUTE AND CHRONIC LOW TEMPERATURE STRESS ON SURVIVAL OF MICE CHALLENGED WITH STAPHYLOCOCCUS AUREUS,
Abstract
Normal and immunized mice were subjected to acute and chronic stress of 2 C ambient temperature. The mice were challenged with varying doses of Staphylococcus aureus, strain Fritchie. Immunization offered significant protection to mice kept at 21 C and to mice that were immunized, challenged and acutely exposed to 2 C in groups. No protection was observed in mice that were immunized, challenged and exposed as individuals to 2 C. Also, immunized mice that were chronically cold exposed at 2 C were not protected against subsequent challenge and showed equivocal mortality ratios compared to the normal controls challenged under the same conditions. (Author) 0
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 1961
- Accession Number
- AD0281747
Entities
People
- Fred Miya
- Stanley Marcus