CUTANEOUS TOXICITY EVALUATION OF AIR FORCE DEVELOPMENT MATERIALS-V

Abstract

Ten Air Force development materials were studied via the prophetic patch test method on laboratory animals to determine the primary irritant effect, gross sensitization index, and gros percutaneous toxicity of these materials. The patch test studies with rabbits indicated that none of the materials was a primary irritant, sensitizer, nor gros systemic poison. Therefore, there was no contraindication to proceeding with a Shelanski repeated insult patch test on human volunteers. The results of the human patch test indicated that all of the materials were safe to use in contact with human skin.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 1962
Accession Number
AD0283982

Entities

People

  • Karl L. Gabriel
  • Morris V. Shelanski

Tags

DTIC Thesaurus Topics

  • Air Force
  • Animals
  • Aqueous Solutions
  • Contracts
  • Epoxy Resins
  • Government Procurement
  • Governments
  • Intensity
  • Irritants
  • Laboratory Animals
  • Materials
  • Materials Laboratories
  • Materials Testing
  • Resins
  • Test Methods
  • Toxicity
  • Volunteers

Readers

  • Toxicology/Environmental Toxicology