RESEARCH ON PROCEDURES FOR THE LOW-TEMPERATURE PRESERVATION OF BLOOD. V. RED CELL VIABILITY STUDIES IN MAN AND RABBITS USING BLOOD FROZEN WITH GLUCOSE AND LACTOSE-GLUCOSE AS PROTECTIVE ADDITIVES

Abstract

The viability of human erythrocytes preserved by rapid free ing and thawing was assayed by procedures including an independent measure of blood volume. The viability of glucose-treated erythrocytes appears to be related to the a ount of additive used and the tim it remains in liquid state con act with t e cells before freezing. Longer periods of equilibration, while yielding higher red cell recovery following thawing, resulted in heavy osmotic destruction of cells on re ching the recipients' circulation. Rabbit ery hrocyt s treated with glucose additive showed poorer recovery following thawing than did human red cells. (Author)

Document Details

Document Type
Technical Report
Publication Date
Apr 01, 1961
Accession Number
AD0286748

Entities

People

  • A.p. Rinfret

Tags

DTIC Thesaurus Topics

  • Additives (Chemicals)
  • Blood
  • Blood Volume
  • Cells
  • Erythrocytes
  • Freezing
  • Low Temperature
  • Recovery
  • Transition Temperature
  • Viability
  • Volume

Fields of Study

  • Biology

Readers

  • Immunology