DESTRUCTION OF CHIMPANZEE KIDNEY CELLS BY SERA FROM PATIENTS WITH ACUTE INFECTIOUS HEPATITIS

Abstract

Destruction of chimpanzee kidney cells by 2 of 12 acute sera from patients with clinical infectious hepatitis was noted. The cellular effect has been seen in serial passage. The destructive agents, tentatively named SAM-1 and SAM-2, have been shown in fluorescent antibody and neutralization tests to be serologically cross-reactive with convalescent serum derived from clinical infectious hapatitis. The agents are resistant to heat treatment at 56 C. for 30 minutes. (Author)

Document Details

Document Type
Technical Report
Publication Date
Dec 01, 1961
Accession Number
AD0287073

Entities

People

  • William D. Hillis

Organizations

  • United States Air Force School of Aerospace Medicine

Tags

DTIC Thesaurus Topics

  • Antibodies
  • Cells
  • Chimpanzees
  • Heat Treatment
  • Hepatitis
  • Neutralization

Fields of Study

  • Biology
  • Medicine

Readers

  • Brain and Cognitive Science; Experimental Psychology; Cognitive Neuroscience
  • Geochemistry
  • Immunology