PYRIDOXAL PHOSPHATE HYDRAZONE AS A MEASURE OF 1,1-DIMETHYLHYDRAZINE CONGENTRATION IN TISSUES
Abstract
A method is described for determining concentrations of 1,1-dimethylhydrazine (UDMH) in tissues. It is based on the spectral absorption of pyridoxal phosphate-UDMH hydrazone. By use of the described method, brain UDMH levels were determined in two groups of rats. Both groups received 120 mg./kg. UDMH; one received additionally 100 mg./kg. pyridoxine hydrochloride. There were no apparent differences in the two groups either in the level of accumulating the hydrazide or in the rate of clearing it. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 01, 1962
- Accession Number
- AD0287077
Entities
People
- Hugh D. Braymer
- Johnie L. Reeves
- Miguel A. Medina
Organizations
- United States Air Force School of Aerospace Medicine