THE HEMAGGLUTINATION-INHIBITION ACTIVITY OF HUMAN PAROTID SALIVA

Abstract

The myxoviruses which include the influenza and mumps viruses can cause the agglutination of a variety of red blood cells. This hemagglutination can take place if the virus attaches itself to the surface of a red blood cell that contains specific viral receptor sites. Such hemagglutination can be prevented, however, by the addition of nonspecific inhibitors or specific inhibitors such as viral antibodies that compete with the virus or block viral receptor sites on the red blood cells. This report is concerned with the extent of the hemagglutination-inhibition activity exhibited by parotid saliva, and whether this inhibition is due to nonspecific factors or to specific viral antibodies. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1962
Accession Number
AD0287192

Entities

People

  • Frank Morrison
  • Irving L. Shklair
  • Max Rosenbaum

Tags

DTIC Thesaurus Topics

  • Agglutination
  • Antibodies
  • Blood
  • Blood Cells
  • Cells
  • Influenza
  • Inhibition
  • Inhibitors
  • Microorganisms
  • Viruses

Fields of Study

  • Biology
  • Medicine

Readers

  • Cardiovascular Physiology
  • Cellular and Molecular Pathways of Apoptosis.
  • Virology (or Medical Virology).