A MATHEMATICAL MODEL FOR THE DISTRIBUTION OF LENGTHS OF CHROMOSOMAL DEFICIENCIES INVOLVING A SPECIFIC LOCUS
Abstract
A mathematical model of random two-hit reakage and deficiency s developed for the condtion that the chromosoml segment lost includes an arbitrary but specifc locus. Both a discrete band model and a continuous chromosome model are considered in presenting theoretical distributions for deficiency lengths, deficiency midpoints, and other relted characteristics. he problem of eimating the location of essential loci is discussed for the continuous model. (AUTHOR)A-287 2809N3 +++Mthematical analys for the determination of breaks and chromosomal recombinations in Drosophia melanogaster to eluidate the mechansm of the origin of chromosoal rearrangements.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1962
- Accession Number
- AD0287280
Entities
People
- B. Wallace
- K.h. Thompson
- W.t. Federer