THE EFFECT OF COLD EXPOSURE ON THE SURVIVAL OF MOCE INOCULATED WITH VIABLE OR HEAT KILLED SALMONELLA TYPHIMURIUM
Abstract
Identifiers: Salmonella typhimurium. Mice exposed to 5 C show an increased susceptibility to the lethal effects of Salmonella typhimurium, strain SR-11A, heat-killed S. typhimurium, or a relatively avirulent strain of Staphylococcus aureus Giorgio. This increase in susceptibility to infection at low environmental temperatures is masked in infections with a more virulent strain of viable S. typhimurium (SR-11). However, with lower doses of the latter, the 25 C exposed mice are at least temporarily more successful in resisting the lethal effects of the disease. The differences in results between infection with SR-11 and SR-11A may be due to the genetic homogeneity and heterogeneity of the two respective cultures. Metabolic changes responsible for the increased susceptibility of the cold exposed animals remain to be investigated. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 01, 1962
- Accession Number
- AD0288686
Entities
People
- J.j. Previte
- L.j. Berry
Organizations
- Bryn Mawr College