THE ABSORPTION OF FATTY ACIDS BY INTESTINAL PERFUSION IN SITU
Abstract
The absorption of lipids by the gastrointestinal tract has been studied by the classical techniques of fat balance studies, the Cori technique, thoracic duct cannulated animals, and histological sections. The in vitro techniques with inverted intestinal sacs and perfusion of isolated intestinal segments have been utilized recently. Some of the limitations and objections to both the previously employed in vitro and in vivo techniques can be overcome by the use of the in situ perfusion technique described by Jacobs and Luper for the study of carbohydrate absorption. Pivalic acid-1-C14 as a model substrate has been shown to be well absorbed by this technique. Preliminary studies in progress indicate absorption of a high molecular weight fatty acid (palmitic). (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Mar 15, 1962
- Accession Number
- AD0289618
Entities
People
- James C. Mcpherson
- William W. Burr
Organizations
- United States Army Biological Warfare Laboratories