EFFECTS OF IPRONIAZID ON AVOIDANCE BEHAVIOR IN THE SLEEP-DEPRIVED RAT
Abstract
Thirteen pairs of rats were run continuously for 5 days in an escape-avoidance situation utilizing a shuttle box. One rat of each pair was treated with iproniazid; the other with s line. The iproniazid group showed a significantly greater number of avoidances per hour during the last 1/2 of the 1st and 2nd days, all of the 3rd day,AND THE FIRST 1/2 OF THE 4TH DAY. Sev ral rats were run in the same apparatus 16 hours/day for 4 weeks with administration of iproniazid after a stable level of avoidances/day had been reached. Some showed an increased rate of avoidance responding with a peak 6 - 11 da s after the 1st injection while others showed no effects. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Nov 30, 1962
- Accession Number
- AD0292710
Entities
People
- Audrey R. Holliday
- William J. Devery
Organizations
- University of Washington