THE SYNTHESIS OF AMINO-1,2-DITHIACYCLANES
Abstract
Cyclic amino disulfides with varying degrees of ring - strain and related dimercaptoamines were prepared. Rearrangement of nitrogen mustardlike intermediates was prevented by blocking the nitrogen with the benzenesulfonyl group prior to the introduction of the sulfur - containing functions. If the nitrogen was not in a position propitious for ring closure and rearrangement, blocking of the nitrogen was unnecessary. Nor were rearrangements of concern when the amino group was introduced subsequent to the introduction of the sulfur functions. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Aug 01, 1962
- Accession Number
- AD0292908
Entities
People
- Harry F. Herbrandson
Organizations
- Rensselaer Polytechnic Institute