STUDIES ON THE METABOLISM OF FATTY ACIDS AND RELATED SUBSTANCES IN ANIMALS EXPOSED TO COLD
Abstract
The development or perfection of techniques in the study of metabolism of fatty acids and related substances in animals exposed to cold was investigated. The experiments were all performed on liver slices from 'male' Wistar rats, 3 1/2 to 6 months old, fed on a standard synthetic diet. Control animals were kept at 25 C. (warm rats); the experimental group was exposed to 0-2 C. (cold rats). The food intake of the cold rats was about 1 1/2 times that of the warm rats, while the water intake of the latter was 1 1/2 times that of the former. During a 10-day experimental period the warm rats gained about 7% in body weight, while the cold rats lost about 6% in the same period. The water content of the whole animal was studied in two warm and two cold rats, and no appreciable difference was found. Certain of the cold rats died with characteristic bodily changes. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1956
- Accession Number
- AD0293173
Entities
People
- David Rapport
Organizations
- Tufts University