THE EFFECT OF PROLONGED COLD EXPOSURE ON HEPATIC LIPOGENESIS
Abstract
Studies of hepatic lipogenesis to rats that have lived in the cold successfully for several months -cold-adapted rats are presented. Liver slices from these cold-adapted rats also showed depressed lipogenesis, but the surprising finding is that this reduction in fatty acid synthesis is not the result of a curtailed hepatic carbohydrate metabolism. Two aspects of hepatic acetate metabolism were studied under these conditions: oxidation of acetate-1-C14 to C14O2 and incorporation of acetate-1-C14 into long chain fatty acids. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 01, 1956
- Accession Number
- AD0293185
Entities
People
- E.j. Masoro
- J.m. Felts
- Sylvia S. Panagos
Organizations
- Tufts University