THE EFFECT OF PROLONGED COLD EXPOSURE ON THE IN VITRO RESPIRATION AND ANAEROBIC GLYCOLYSIS OF RAT LIVER

Abstract

Liver slices were prepared from rats that had been exposed to cold (5!1 C.) for intervals of 2, 4, 6 or 9 weeks, and assays were made for respiratory rate and the rate of anaerobic glycolysis. The results of the respiration experiments indicated the first 4 weeks' cold exposure was associated with increasing QO2 values, whereas exposure longer than 4 weeks wasASSOCIATED WITH WITH QO2 values that returned toward the control value. The results indicated further that the exact nature of the substances being metabolized in the conventional tissue slice experiment was unknown. The results of the anaerobic experiments indicated the rate of anaerobic glycolysis decreased progressively as the duration of cold exposure was increased. (Author)

Document Details

Document Type
Technical Report
Publication Date
Jun 01, 1957
Accession Number
AD0293187

Entities

People

  • John P. Hannon

Tags

DTIC Thesaurus Topics

  • Biological Sciences
  • Glycolysis
  • Intervals
  • Metabolism
  • Respiration

Readers

  • Aquatic Ecology
  • Mathematics or Statistics
  • Toxicology/Environmental Toxicology