THE VENTILATORY RESPONSE TO CARBON DIOXIDE AND TO OXYGEN AFTER ACCLIMATIZATION TO CARBON DIOZIDE

Abstract

A chawber has been designed so that dogs can be exposed for prolonged periods to abnormal atmospheres. The concentrations of CO2 and O2 are continuously controlled and recorded. Exposure of dogs to approximately 3 percent CO2 in air for 6 days or more resulted in a decrease in the ventilatory response to CO2. In control dogs the breathing of 50 per cent oxygen for 30 minutes was associated with a slight to moderate increase in ventilation without a significant change in arterial pCO2. After acclimatization to CO2 oxygen breathing was associated with Little change in ventilation but with a rise in arterial pCO2.

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Document Details

Document Type
Technical Report
Publication Date
Nov 01, 1962
Accession Number
AD0293993

Entities

People

  • Richard M. Peters
  • Thomas B. Barnett

Organizations

  • Air Force Research Laboratory

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Air Force
  • Atmospheres
  • Biomedical Research
  • Carbon Dioxide
  • Contracts
  • Controlled Atmospheres
  • Government Procurement
  • Heat Transfer
  • Laboratory Animals
  • Measurement
  • North Carolina
  • Physiology
  • Respiration
  • Respiration Disorders
  • Respiratory Physiological Phenomena
  • Thermal Conductivity
  • Ventilation

Readers

  • Cardiovascular Physiology