THE ROLE OF THE THYROID IN THE METABOLIC RESPONSE TO LOW TEMPERATURE
Abstract
The requirement for thyroxin in chemical regulation of heat production was studied by te ting the metabolic response of curarized rats to cold exposure at varying periods after thyroidectomy. Sprague-Dawley rats were kept at 5 and 28 C. The metabolic response to cold in curarized rats is not directly dependent upon the amount of circulating thyroxin because the response persists when thyroxin stores are depleted. Cold-adapted rats reduced their food intake and lost weight following thyroidectomy, but maintained a high metabolism at 5 C. (Author)
Document Details
- Document Type
- Technical Report
- Publication Date
- May 01, 1957
- Accession Number
- AD0294035
Entities
People
- A.c.l. Hsieh
- L.d. Carlosn
Organizations
- University of Washington