Screening Studies with Variola Virus
Abstract
An investigation was initiated to screen variola virus. The experimental data are concerned with methods of assaying the virus quantitatively, determining optimal conditions for culture growth, and the effect of various physical and chemical reagents on its viability. Viability after lyophilization and the storage stabilities of both liquid and dried organisms were noted. Monkeys, as a test host, were infected by the parenteral, oral, intranasal, and aerosol routes. The disease picture in these animals was similar to that of human infections. The findings of viral cytopathogenicity and propagation of the organisms in different tissue cultures are given.
Document Details
- Document Type
- Technical Report
- Publication Date
- Oct 01, 1958
- Accession Number
- AD0322280
Entities
People
- Nicholas Hahon
Organizations
- United States Army Biological Warfare Laboratories