RESEARCH IN FLUORO-NITRO COMPOUNDS

Abstract

The conversion of carbonyl groups to gem-difluoramines using difluoramine and H2SO4, has been extended to polynitroketones, gamma-diketones, and ketoesters. The addition of difluoramine to simple unbranched olefins was accomplished using H2SO4, methanesulfonic acid, or BF3-H3PO4 complex as the catalyst. The latter catalyst was also applied to the addition of difluoramine to an acetylene. Aqueous fluorination of amides and carbamates, resulting in the displacement of H or CO groups on N by F, was extended to a series of difunctional and cyclic substrates. The acidcatalyzed reaction of ethyl N-fluorocarbamate with aldehydes gave simple addition and replacement of the resulting hydroxyl group. This carbamate also added to olefins. It reacted with H2SO4 to give the N-fluoroammonium salt. The nitration of N-fluoro-N-n-butylcarbamate gave N-fluoro-N-nitro-n-butylamine. Gamma-difluoraminobutyric acid was converted by the Curtius reaction sequence to the isocyanate. A gemdifluoramine was reduced with LiAlH to the monoamine. (Author)

Document Details

Document Type
Technical Report
Publication Date
Oct 01, 1962
Accession Number
AD0332447

Entities

People

  • K. Baum
  • V. Grakauskas

Organizations

  • Aerojet Rocketdyne Holdings

Tags

DTIC Thesaurus Topics

  • Acetylenes
  • Aldehydes
  • Alkynes
  • Amines
  • Carbamates
  • Catalysts
  • Chemical Compounds
  • Conversion
  • Displacement
  • Fluorination
  • Isocyanates
  • Nitration
  • Nitro Compounds
  • Organic Compounds
  • Sequences
  • Substrates

Fields of Study

  • Chemistry

Readers

  • Organic Chemistry