THE DETECTION OF ANTICHOLINESTERASE AGENTS USING AN ENZYME INHIBITION REACTION. PART 8. DEVELOPMENT OF A PORTABLE AUTOMATIC ALARM (MODEL VIII)
Abstract
A portable automatic alarm (Model VIII) has been designed for the detection of anticholinesterases. It operates from a 24 volt battery at a power consumption of 12 watts, and, excluding the battery, measures 8 in. x 8 in. x 14 in. and weighs 18 lb. The alarm utilises the enzyme inhibition reaction, the enzyme being pseudo-cholinesterase obtained from horse serum. Three different reagent solutions are required, and these are used in a continuous flow system with continuous sampling of the suspect atmosphere. A photo electric monitoring of the colour density of the reaction product activates the alarm system when the colour density is decreased. In preliminary experiments in the gas chambers the alarm re sponded to 0.015 microgram/1 of GB within fifteen seconds. It is anticipated that this design of alarm may be applicable in principle to other chemical detection systems employing one or more reagent solutions, and in which detection occurs as the result of a change in colour density of the reaction product.
Document Details
- Document Type
- Technical Report
- Publication Date
- Feb 25, 1963
- Accession Number
- AD0340089
Entities
People
- A. M. Kinnear