PHYSICAL PERFORMANCE FOLLOWING INHALATION OF GB

Abstract

''Maximal'' work tests have been carried out on 20 subjects, and submaximal work tests on a further 20 subjects, using an electrically braked bicycle ergometer. Following the inhalation of GB (nominal dose 5 ug/kg) there was a small decrease in ''maximal'' rate of working relative to control days; following the inhalation of isopropanol, there was a small increase in the rate of working relative to control days. Sub-maximal work tests showed an increase of oxygen consumption following inhalation of isopropanol. The ''test series showed no increase of ventilation following inhalation of GB, implying that the increase in O2 consumption was achieved by an increased efficiency of gas transfer in the lungs; no change of pulse rate, rise of body temperature, respiratory rate, tidal volume, respiratory quotient, or ventilatory equivalent for oxygen was observed following administration of GB. The group inhaling isopropanol showed a significant increase of extraventilation in the 15 min following exercise on the test day; this response was not shown by those inhaling GB. Local symptoms of GB inhalation were unnoticed during vigorous exercise.

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Document Details

Document Type
Technical Report
Publication Date
May 01, 1963
Accession Number
AD0343262

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  • R. J. Shephard

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