THE ACUTE TOXICITY OF DIFLUORAMINO COMPOUNDS AND THEIR INTERMEDIATES.

Abstract

Twenty-six chemicals, about half organic-NF2 compounds, were tested for acute oral and/or inhalation toxicity in rats. None was innocuous and none was a violet poison; as a class the difluoramines were toxic enough to warrant special handling, especially with respect to vapor inhalation. No meaningful pathological data were collected. The acute oral toxicities of the difluoramine compounds, however, correlated roughly with that of fluoride ion. There was no systematic difference in toxicity between the vicinal and the geminal bis(difluoramino) compounds. The equipment, experimental techniques, and calculation methods used are reviewed. (Author)

Document Details

Document Type
Technical Report
Publication Date
Nov 29, 1966
Accession Number
AD0377298

Entities

People

  • Kenyon Stevenson

Tags

DTIC Thesaurus Topics

  • Chemical Compounds
  • Fluorides
  • Fluorine Compounds
  • Toxicity

Fields of Study

  • Chemistry

Readers

  • Organic Chemistry
  • Systems Analysis and Design
  • Toxicology/Environmental Toxicology