RELATION BETWEEN THE ELECTRORETINOGRAM (ERG) AND SINGLE CELL ACTIVITIES IN THE RETINA

Abstract

Attempt at identifying the cell types that make sources of the ERG components is continued. Of the three groups of responses recorded from single units in the frog's retina, only the Group-II responses were left suspected to be constituents of the ERG, but the present work excludes this possibility, since it is probable that the responses in question arise from the soma and/or dendrites of ganglion cells that contribute little to the ERG. The failure to re cord any constituents of the ERG in the frog led research in two directions. One is the effort to make intracellular recording possible from cell types other than those already studied. A technique of ''harpooning'' single cells with pipets at high momentary acceleration is being tested and will make a subject in the coming year. The other is to apply the conventional technique to materials other than the frog and see if the localization of ERG constituents is possible in these materials. Among several animals examined, the carp is subject to a more thorough test. Studied are properties of Group-III responses (S-potentials), and the spatial distribution of ERG components in the focal and non-focal regions of the retina.

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Document Details

Document Type
Technical Report
Publication Date
Feb 01, 1963
Accession Number
AD0402961

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  • Tsuneo Tomita

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  • Keio University

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