EFFECTS OF RADIATIONS ON CELL DIVISION AND CHROMOSOMES IN ANIMALS
Abstract
Effects of radiations on cell division and chromosomes in animals were studied from various stand points. X- and beta-irradiations on grasshopper spermatocytes were investigated using various chemicals with special regards to the radioprotection. The effects of single or repeated X-irradiation on chromosomes of human in vitro cell line were studied. Genetic studies of anomalies in the mouse populations whose ancestors have received X-irradiation were investigated. Effects of X-rays on the spermatogenesis of Drosophila were studied and the effects of gamma-irradiation on mating type of Paramecium were studied using P. polycarium which has the binary mating type. Many new clones were obtained by the application of gamma-irradiation. These clones were very useful to analyses the genetic behaviour of Paramecia and further studies are in progress. Immunological response of lethally irradiated mice which receive injection of heterologous spleen cells was studied. Histological observations on spleens were carried out as a supplemental experiment. The effects of X-irradiation on the pregnancy rate in mice received polyovulation treatment were investigated. The implantation of hormone-induced polyovulated eggs, 25 X-irradiation is effective.
Document Details
- Document Type
- Technical Report
- Publication Date
- Dec 14, 1962
- Accession Number
- AD0403109
Entities
People
- Sajiro Makino
Organizations
- Hokkaido University