THE PREPARATION OF CARBON-14 LABELED TETRAMETHYL AMMONIUM BROMIDE
Abstract
Carbon-14 labeled tetramethylammonium bromide was prepared via the condensation of C-14 methyl bromide with trimethylamine using high vacuum techniques. Unrecrystallized product yields, in the range of 100% of theory (based on methyl bromide), are independent of variations in excess quantitites of trimethylamine. C-14 methyl bromide is effectively derived from an intermixture of C-14 methyl iodide with methyl bromide in the ratio of 1:350. A series of preparations from aliquots of the stock CH3I/CH3Br mixture result in reproducible yields and specific activities of 1.8% average deviation.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 1963
- Accession Number
- AD0403407
Entities
People
- Andrew F. Smetana
- Jerome Haberman
- Thomas C. Castorina
Organizations
- Picatinny Arsenal