A COMPARATIVE STUDY OF THE INTRANASAL AND AEROSOL METHODS OF VACCINATION AGAINST INFLUENZA

Abstract

The reactogenicity of influenza vaccines during the aerosol method of immunization was lower than during the intranasal method. Along with this there were no temperature reactions over 37.5 noted. Other symptoms of vaccinal reaction (head cold, headache, sneezing and others) were ob served less seldom during the aerosol method and were not so sharply expressed. The egg tissue and egg-tissue combined type A2 vaccine provided the best indices of adaptability and immunologi cal effectiveness. Comparative data testifies to the future prospects and convenience of the aerosol method for the immunization of large masses of the population with live influenza vac cine, however for a conclusive evaluation of it, further investigations are required.

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Document Details

Document Type
Technical Report
Publication Date
Apr 01, 1963
Accession Number
AD0405017

Entities

Organizations

  • United States Army Biological Warfare Laboratories

Tags

DTIC Thesaurus Topics

  • Antibodies
  • Biological Laboratories
  • Body Temperature
  • Diseases And Disorders
  • Equations
  • Freeze Drying
  • Immunization
  • Infectious Diseases
  • Influenza
  • Medical Personnel
  • Military Medicine
  • Pain
  • Particle Size
  • Tissues
  • Vaccination
  • Vaccines
  • Viruses

Readers

  • Immunology
  • Infectious Disease/Epidemiology
  • Systems Analysis and Design

Technology Areas

  • Biotechnology