ISOLATION OF THE POLYHEDER VIRUS AND THE NATURE OF POLYHEDERS

Abstract

By treatment with dilute alkali and centrifuging, the substance of the polyheders found in moth larvae infected with the polyheder disease could be separated into a water-insoluble protein and a water-soluble nucleoprotein. The two moieties could be differentiated chemically on the basis of their phosphorus content, which was low in the case of the protein and high in the case of the nucleoprotein. It is concluded on the basis of experiments on insects that the nucleoprotein rather than the protein, which had been mistaken for the virus in earlier work, must be regarded as the causative factor of the virus infection known as polyheder disease. The nucleoprotein is likened to the smallpox soluble antigen, which can be separated by similar methods from the smallpox virus.

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Document Details

Document Type
Technical Report
Publication Date
Feb 26, 1963
Accession Number
AD0405031

Entities

People

  • Gernot Bergold

Organizations

  • Joint Publications Research Service

Tags

Communities of Interest

  • Air Platforms
  • C4I

DTIC Thesaurus Topics

  • Acetic Acid
  • Cells
  • Chemical Synthesis
  • Chemistry
  • Elementary Particles
  • Equations
  • Habitats
  • Lepidoptera
  • Measurement
  • Molecular Weight
  • Molecules
  • Plastic Explosives
  • Precipitation
  • Specific Volume
  • Two Dimensional
  • Virion
  • Viruses

Readers

  • Analytical Chemistry
  • Vector-Borne Disease and Entomology
  • Virology (or Medical Virology).