THE SIGNIFICANCE OF THE WHITE BLOOD CORPUSCLES IN ANTHRAX INFECTIONS

Abstract

In rabbits and sheep a series of vaccination processes are produced and a histological examination done. The results were as follows: the leucocyte and lymphocyte emigration is in vaccine inoculation stronger than in virulent infection. Previous immunization considerably aids the local leucocytosis after inoculation with virulent or vaccine bacteria, but the reaction of the vaccine is stronger. Phagocytosis is not promoted by immunization and they are exclusively cleared away by means of extra-cellular annihilation. The vaccine bacilli are after immunization cleared away as well by means of phagocytosis as by extra cellular digestion. This process is very rapid; already after nine hours the bacilli inoculated in immune rabbits have disappeared. This process takes 24 hours in immune sheep, the vaccine bacteria are here sooner annihilated than the virulent matter.

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Document Details

Document Type
Technical Report
Publication Date
Apr 02, 1963
Accession Number
AD0405101

Entities

People

  • F. De Moulin

Organizations

  • Joint Publications Research Service

Tags

DTIC Thesaurus Topics

  • Animals
  • Biological Laboratories
  • Blood
  • Cells
  • Connective Tissue
  • Dutch Language
  • Government Procurement
  • Immunization
  • Immunomodulation
  • Infection
  • Laboratory Animals
  • Leukocytes
  • Lymphocytes
  • Tissues
  • Vaccination
  • Vaccines
  • Wound Infections

Fields of Study

  • Biology
  • Medicine

Readers

  • Immunology

Technology Areas

  • Biotechnology