EXPERIMENTAL STUDY OF ACUTE AND CHRONIC INJURY TO RENAL TUBULES

Abstract

A study of the normal ultrastructure of the rat kidney was undertaken as a basis for a study of the serial morphologic changes in acute tubular necrosis. By electron microscopy, a close structural relationship between endoplasmic reticulum and cytosomes and between cytosomes and the Golgi region was established. The tytosomes involved are acid-phosphatase containing and may be regarded, preliminarily, as lysosomes. The technique of nephron-dissection has been perfected in the laboratory and is being applied to normal kidney tissues.

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Document Details

Document Type
Technical Report
Publication Date
Jun 30, 1963
Accession Number
AD0405883

Entities

People

  • Ivan L. Bennett Jr.

Organizations

  • Johns Hopkins University

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Biomedical Research
  • Blood Transfusions
  • Cell Membrane
  • Cells
  • Cellular Structures
  • Cytoplasm
  • Electron Microscopes
  • Electron Microscopy
  • Endoplasmic Reticulum
  • Government Procurement
  • Health Services
  • Inclusions
  • Medical Laboratories
  • Microscopy
  • Necrosis
  • New York
  • Pathology

Readers

  • Cellular and Molecular Pathways of Apoptosis.
  • Systems Analysis and Design
  • Virology (or Medical Virology).

Technology Areas

  • Microelectronics