RESEARCH ON PROCEDURES FOR THE LOW-TEMPERATURE PRESERVATION OF BLOOD

Abstract

This research represents a continuing search for protective additives in the freezing of whole blood or red cell suspensions. The data presented show that high recovery can be achieved of intact red cells, that these cells have high survival after transfusion, and that reproducible results can be achieved with pint quantities. Clinical trials are needed to establish the suitability of red cells preserved in this way in persons requiring them, and studies are needed of the physiological acceptability of these additives in the concentrations that would be administered if post-thaw separation were not used. Red cell preparations that can be infused without post-thaw processing have been studied and in addition, an increased effort on developing a rapid and simple post-thaw separation procedure has been made.

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Document Details

Document Type
Technical Report
Publication Date
Mar 31, 1963
Accession Number
AD0407924

Entities

People

  • A. P. Rinfret

Tags

Communities of Interest

  • Ground and Sea Platforms

DTIC Thesaurus Topics

  • Albumins
  • Aqueous Solutions
  • Blood
  • Blood Substitutes
  • Blood Volume
  • Cells
  • Health Services
  • Heat Transfer
  • Ion Exchange
  • Ion Exchange Resins
  • Low Temperature
  • Mannitol
  • Materials
  • Mixtures
  • Resins
  • Rodents
  • Water

Readers

  • Aerospace Test and Evaluation
  • Immunology