Mechanisms of Smooth Muscle Relaxation Through the Anodal Current Stimulation
Abstract
Studies on the mechanisms of the smooth muscle relaxation through the anodal current stimulation were continued. In order to conduct the experiment on the mammalian smooth muscle, its normal action potential was studied. Ureter was selected as the material because the intracellular action potential of this tissue has rarely been studied. Action potential of the ureter smooth muscle shows a slow plateau phase, which indicates that a single cell is responsible for the plateau formation. The effect of repetitive stimulation on this muscle was studied and it was found that the refractory period of the ureter smooth muscle cell was very long compared to other smooth muscles. The effect of the sodium deficiency on the pattern of action potential were also studied, and the results indicated that the action potential of the smooth muscle of the ureter can be satisfactorily explained from the basis of sodium hypothesis.
Document Details
- Document Type
- Technical Report
- Publication Date
- Jun 14, 1963
- Accession Number
- AD0409502
Entities
People
- Hiroshi Irisawa
Organizations
- Hiroshima University