THE EXPLANATION OF PATHOGENESIS OF JAPANESE ENCEPHALITIS (JE) VIRUS AND THE ESTABLISHMENT OF AN ATTENUATED STRAIN OF JE VIRUS COMPLETELY A VIRULENT TO MAN. PART III. STUDIES ON JAPANESE ENCEPHALITIS VIRUS INFECTION WITHIN CULTIVATED ANIMAL CELLS BY THE APPLICATION OF FLUORESCENT ANTIBODY TECHNIQUE.

Abstract

Process of Japanese B encephalitis virus infection cultivated animal cells. i.e. hamster kidney, porcine kidney and HeLa cells was fol lowed by fluorescent antibody technique. The infection was adjusted to obtain multiplicities 5-10 for each system Viral antigen was initial ly detected in perinuclear cytoplasm at 10 - 15 hrs of infection. then numbers of the antigen producing cells increased and antigen producing area expanded within cytoplasm.

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Document Details

Document Type
Technical Report
Publication Date
Jan 31, 1963
Accession Number
AD0409936

Entities

People

  • Akira Oya

Organizations

  • Istituto Superiore di Sanità

Tags

Communities of Interest

  • Biomedical

DTIC Thesaurus Topics

  • Antibodies
  • Antigens
  • Arbovirus Infections
  • Arthropod-Borne Encephalitis
  • Cell Nucleus
  • Cells
  • Cytoplasm
  • Encephalitis
  • Epithelial Cells
  • Government Procurement
  • Infection
  • Materials
  • Tissue Culture
  • United States
  • Virus Diseases
  • Viruses
  • Wound Infections

Fields of Study

  • Biology

Readers

  • Virology (or Medical Virology).