A POSSIBLE SOURCE OF SECONDARY INVADING STAPHYLOCOCCI IN SALMONELLA INFECTED MICE EXPOSED TO ACUTE COLD
Abstract
In a effort to determine the origin of the staphylococci known to invade the deep tissues (liver, spleen, kidneys, lungs and heart) of mice exposed continuously to 5 deg C in individual compartments without bedding, the intestinal tract was freed of these organisms, as judged by absence of growth when fecal suspensions were inoculated into selective media. Substitution of 0. 01 N hydrochloric acid for drinking water eliminated staphylococci within a few days, yet the incidence of tissue invasion was unaltered. The coagulase negative strains normally present in feces and in tissues persisted in tissues even though the intestine was seeded with a coagulase positive strain by feeding contaminated food. Cultures from the external nares continued unaltered. This suggests that the respiratory tract is a possible origin of the staphylococci found in tissues of the cold stressed mice.
Document Details
- Document Type
- Technical Report
- Publication Date
- Apr 01, 1963
- Accession Number
- AD0410404
Entities
People
- G. J. Miraglia
- L. J. Berry
Organizations
- Bryn Mawr College